Hereditary coproporphyria.
نویسندگان
چکیده
Hereditary coproporphyria, a form of acute hepatic porphyria, is a rare Mendelian autosomal dominant inherited condition with incomplete penetrance. The acute attack is usually followed by complete remission, but death may occur. Latent cases are recognised, and the characteristic neurovisceral symptoms and signs are shared by many other conditions. Acute porphyria should be considered in the differential diagnosis of any patient presenting with abdominal pain and neuropsychiatric upset.
منابع مشابه
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A 9-year-old boy with mental deterioration and epilepsy suffered an acute attack of hereditary coproporphyria associated with worsening of seizure control. Leucocyte coproporphyrinogen oxidase activity was undetectable in the patient during this attack, and was reduced in his mother, a latent case. The complex relationship between porphyria, epilepsy, and anticonvulsant drugs is discussed.
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OBJECTIVE We report a successful treatment with lamotrigine of a patient with hereditary coproporphyria presenting with affective and psychotic symptoms. CASE REPORT M.F., a 38-year-old, single woman was admitted to an acute psychiatric ward because of suddenly emerging psychosis. Ms F's hereditary coproporphyria was diagnosed 9 years before the current admission. While on treatment with olan...
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ورودعنوان ژورنال:
- The Ulster Medical Journal
دوره 63 شماره
صفحات -
تاریخ انتشار 1994